Clinical Trial

Tongfu Qinghua Decoction Enema and Ruyi Jinhuang Powder for Acute Pancreatitis

Completed
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Summary
Acute pancreatitis is an inflammatory condition that commonly causes abdominal pain, abdominal distension, impaired gastrointestinal function, and elevated pancreatic and inflammatory biomarkers. Although conventional medical treatment can stabilize most patients, recovery of gastrointestinal function and relief of local inflammation may remain slow. This completed, single-center, randomized controlled study evaluated whether adding Tongfu Qinghua Decoction administered by enema and Ruyi Jinhuang Powder applied externally to conventional medical treatment could improve clinical recovery in adults with acute pancreatitis. A total of 100 participants aged 18 to 75 years were randomly assigned in a 1:1 ratio to receive either conventional medical treatment alone or conventional medical treatment combined with Tongfu Qinghua Decoction enema and external application of Ruyi Jinhuang Powder. Both groups received treatment for 5 days. The study evaluated overall clinical response, length of hospital stay, time to relief of abdominal pain and abdominal distension, recovery of bowel function, time to first food intake, serum and urinary amylase levels, C-reactive protein, procalcitonin, and treatment-related adverse events.
Trial Details
NCT Number NCT07712081
Lead Sponsor The Third Affiliated Hospital of Wenzhou Medical University
Conditions Acute Pancreatitis
Enrollment 100 participants
Start Date 2023-10-01
Primary Completion 2025-08-30 (estimated)
Study Completion 2025-09-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-17