Clinical Trial

Individualized Supramaximal Stimulation Current During Continuous Neuromonitoring in Thyroid Surgery

Study acronym: CIONM-SSC
Completed
View on ClinicalTrials.gov →
Summary
Continuous intraoperative neuromonitoring (C-IONM) is increasingly used during thyroid surgery to detect early changes in recurrent laryngeal nerve function and reduce the risk of nerve injury. Current clinical practice recommends the use of fixed supramaximal stimulation currents; however, these recommendations are based on limited experimental evidence and may not account for individual variability between patients. This retrospective observational cohort study aims to determine patient-specific supramaximal stimulation currents (SSC) during C-IONM and to evaluate whether individualized stimulation provides monitoring quality comparable to conventional fixed-current stimulation while potentially reducing unnecessary stimulation intensity. The study also investigates factors influencing electromyographic response amplitudes during surgery and assesses the safety of individualized stimulation parameters.
Trial Details
NCT Number NCT07710365
Lead Sponsor Medical University of Gdansk
Conditions Thyroid Disease
Enrollment 623 participants
Start Date 2020-06-18
Primary Completion 2024-07-25 (estimated)
Study Completion 2025-02-11 (estimated)
Updated on ClinicalTrials.gov 2026-07-17