Closed Incision NPWT to Prevent Wound Complications Post-ECMO

Patients undergoing extracorporeal membrane oxygenation (ECMO) are at increased risk of wound complications at the vascular access site after decannulation. These complications may delay recovery and increase healthcare burden. Closed incision negative pressure wound therapy (NPWT) may improve wound healing by reducing fluid accumulation and supporting the incision. This study evaluates whether prophylactic NPWT reduces wound complications compared to standard wound care following ECMO decannulation.

NCT Number	NCT07709546
Lead Sponsor	St. Antonius Hospital Collaborators: St. Antonius Onderzoeksfonds, St. Antonius innovatiefonds
Conditions	ExtraCorporeal Membrane Oxygenation (ECMO), Wound Complications, Surgical Site Infection (SSI)
Enrollment	144 participants
Start Date	2026-07-13
Primary Completion	2028-11-18 (estimated)
Study Completion	2029-03-18 (estimated)
Updated on ClinicalTrials.gov	2026-07-16