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Transcranial Direct Current Stimulation for Long COVID Brain Fog and Fatigue

Study acronym: NEUROSTIM-LC
StatusNot Yet Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary endpoints added 3 → 6 primary endpoints
See other at-risk trials from University of Las Palmas de Gran Canaria

Record History

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  1. Primary endpoint(s) modified
    • Secondary endpoints: 6 to 7
    v2
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Long COVID can cause persistent symptoms such as fatigue, cognitive difficulties commonly described as brain fog, reduced exercise tolerance, and impaired quality of life. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that may help modulate brain activity in regions involved in cognition, fatigue, and executive function. The NEUROSTIM-LC study will evaluate the feasibility and potential effects of repeated tDCS sessions in adults with long COVID presenting fatigue and/or brain fog. Participants will receive 30 sessions of tDCS applied over the left dorsolateral prefrontal cortex. Assessments will be performed before and after the intervention to evaluate changes in quality of life, fatigue, cognitive function, brain metabolism, physical performance, autonomic function, sleep quality, psychological symptoms, respiratory function, and blood biomarkers.
Trial Details
NCT Number NCT07709234
Lead Sponsor University of Las Palmas de Gran Canaria
Collaborators: Fundación Canaria Instituto de Investigación Sanitaria de Canarias, Canary Islands Health Service
Conditions
(from sponsor)		 Long COVID, Post-COVID Conditions, Fatigue, Cognitive Dysfunction
Related terms Cognitive Dysfunction, Fatigue, Mental Fatigue, Post-Acute COVID-19 Syndrome
Enrollment 20 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov