Clinical Trial

"Comparison of of Volume-Controlled Ventilation and Pressure-Controlled Ventilation Modes in Laparoscopic Cholecystectomy"

Study acronym: VCV VS PCV
Active, Not Recruiting
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Summary
This randomized controlled trial compares volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) in adult patients undergoing elective laparoscopic cholecystectomy under general anesthesia. The study evaluates the effects of both ventilation modes on static lung compliance and end-tidal carbon dioxide (EtCO₂) at predefined intraoperative time points. The objective is to determine whether pressure-controlled ventilation provides improved respiratory mechanics and more effective ventilation compared with volume-controlled ventilation during laparoscopic surgery.
Trial Details
NCT Number NCT07709039
Lead Sponsor Mehreen Mirza
Conditions Cholelithiases, Laparoscopic Cholecystectomy, General Anaesthesia
Enrollment 60 participants
Start Date 2026-01-01
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-07-20 (estimated)
Updated on ClinicalTrials.gov 2026-07-16