Clinical Performance and Fit of 3D-Printed Versus Milled Endocrowns: An 18-Month Trial

The goal of this clinical trial is to learn whether 3D-printed resin composite endocrowns perform as well as milled resin composite endocrowns in restoring endodontically treated teeth. It will also learn how well the restorations fit over time. The main questions it aims to answer are: Do 3D-printed endocrowns and milled endocrowns show different clinical performance? Do 3D-printed endocrowns and milled endocrowns differ in restoration fit over 18 months? Researchers will compare two fabrication methods: Additive manufacturing: 3D-printed resin composite endocrowns. Subtractive manufacturing: milled resin composite endocrowns. Participants will: Be recruited from the Conservative Dentistry Department, Faculty of Dentistry, October 6 University. Receive tooth preparation after confirmation of satisfactory root canal treatment. Have their teeth prepared using standardized endocrown guidelines by one calibrated operator. Have digital scans taken of the prepared tooth, opposing arch, and bite registration. Have restorations designed digitally and then assigned randomly to one of the two groups. Receive a temporary restoration until the final endocrown is ready. Have the final restoration tried in for fit, contacts, and occlusion before cementation. Have a baseline post-cementation scan taken for fit assessment. Return for follow-up visits at baseline, 6 months, 12 months, and 18 months. Be evaluated at each visit using Modified FDI criteria and 3D digital superimposition for fit analysis.

NCT Number	NCT07708077
Lead Sponsor	October 6 University
Conditions	Clinical Performance of Endodontically Treated Teeth Restored With Endocrowns, Restoration Fit of Endodontically Treated Teeth With Endocrowns
Enrollment	52 participants
Start Date	2026-11-01
Primary Completion	2028-11-01 (estimated)
Study Completion	2028-12-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-21