Clinical Trial

Silver Nanoparticle-Coated Orthodontic Brackets for Preventing Enamel Demineralization

Study acronym: AgBracket
Completed
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to learn whether orthodontic brackets coated with silver nanoparticles can help prevent early damage to tooth enamel in people receiving fixed braces. The main question it aims to answer is: -Do silver nanoparticle-coated brackets help reduce enamel demineralization (the early stage of tooth decay) compared with standard stainless steel brackets? Researchers will compare silver nanoparticle-coated brackets with standard stainless steel brackets. Each participant will receive both types of brackets on different teeth so that the results can be compared within the same person. Participants will: * Receive fixed orthodontic treatment as planned. * Have both silver nanoparticle-coated and standard stainless steel brackets placed on different teeth. * Attend routine orthodontic appointments. * Have premolar teeth that were already planned for extraction as part of their orthodontic treatment removed after one month so researchers can examine the tooth enamel around the brackets.
Trial Details
NCT Number NCT07707336
Lead Sponsor Ajman University
Conditions Enamel Demineralization, White Spot Lesions
Enrollment 16 participants
Start Date 2024-09-20
Primary Completion 2025-04-29 (estimated)
Study Completion 2025-05-23 (estimated)
Updated on ClinicalTrials.gov 2026-07-16