Blinding Integrity Assessment Using Rotational Field Transcranial Magnetic Stimualtion (rfTMS) in Healthy Adults

This study evaluates the effectiveness of an improved blinding method using rotational field transcranial magnetic stimulation (rfTMS) delivered through a multi-channel deep coil system (Brainsway, Jerusalem, Israel). Healthy volunteers receive a single session of either Active or Sham stimulation over the medial prefrontal cortex. The study assesses whether the Sham condition sufficiently masks the sensory characteristics of Active stimulation. Findings will support the optimization of blinding procedures for future deep TMS (dTMS) trials.

NCT Number	NCT07706790
Lead Sponsor	Soroka University Medical Center Collaborators: Ben-Gurion University of the Negev
Conditions	Healthy Volunteers
Enrollment	60 participants
Start Date	2025-09-09
Primary Completion	2025-12-18 (estimated)
Study Completion	2026-07-05 (estimated)
Updated on ClinicalTrials.gov	2026-07-16