Large-Scale Evaluation of a Clinical Decision Tree for the Management of Low-Energy Thoracic and Lumbar Vertebral Compression Fractures.

Percutaneous vertebroplasty is widely used for low-energy vertebral compression fractures, but its clinical benefits remain debated. Studies and meta-analyses have reported mixed results, while complications occur in a significant proportion of patients, highlighting the importance of careful patient selection. To standardize management, a clinical decision tree was developed based on patient age, MRI findings, pain severity (VAS), and radiological deformity.

NCT Number	NCT07706439
Lead Sponsor	University Hospital, Grenoble
Conditions	Thoracolumbar Low-energy Vertebral Compression Fractures
Enrollment	400 participants
Start Date	2026-07-15
Primary Completion	2027-07-15 (estimated)
Study Completion	2027-07-15 (estimated)
Updated on ClinicalTrials.gov	2026-07-17