Sex-Divergent Effects of Magnesium L-Threonate Supplementation on Sleep Quality, Cognitive Performance, and Neuromuscular Function in Healthy Adults

This study examined the effects of six weeks of magnesium L-threonate (MgT) supplementation on sleep quality, cognitive performance under experimentally induced mental fatigue, neuromuscular function, and psychophysiological outcomes in healthy adults. Biological sex and weight status were examined as pre-specified moderating variables.

NCT Number	NCT07706283
Lead Sponsor	Barry University
Conditions	Healthy Adults; Cognitive Performance; Sleep Quality; Neuromuscular Function
Enrollment	81 participants
Start Date	2025-12-01
Primary Completion	2026-03-19 (estimated)
Study Completion	2026-03-19 (estimated)
Updated on ClinicalTrials.gov	2026-07-15