Naproxen and Lidocaine Gel Combination for Rib Fracture

This study evaluates whether adding a topical gel containing naproxen and lidocaine to routine intravenous analgesic treatment improves pain relief in adults with isolated traumatic rib fractures presenting to the emergency department. Participants are randomly allocated to receive either standard intravenous dexketoprofen alone or dexketoprofen combined with topical naproxen-lidocaine gel. Pain intensity is measured repeatedly during the first hour after treatment using the Numerical Rating Scale (NRS). The study also examines the need for additional rescue analgesia and monitors treatment-related adverse events to determine the effectiveness and safety of this multimodal analgesic strategy.

NCT Number	NCT07706036
Lead Sponsor	Ankara City Hospital Bilkent
Conditions	Thorax; Fracture, Rib Fracture, Pain Management
Enrollment	110 participants
Start Date	2024-01-01
Primary Completion	2024-07-01 (estimated)
Study Completion	2024-07-02 (estimated)
Updated on ClinicalTrials.gov	2026-07-20