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Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study

StatusEnrolling by Invitation
PhasePhase 2
Started2026-08-07
View on ClinicalTrials.gov ↗

Amendment history

2026-08-10
notable
Study Status, Contacts/Locations v1
Enrolling by invitation only
Start dateestimated 2026-07→confirmed 2026-08-07
Study sitescontacts updated at 1 of 1 site
2026-07-10
minor
Original filing
This research is studying whether mental functions take place during different levels of anesthesia, using a commonly used drug (either dexmedetomidine \[with propofol in some participants\] or ketamine), which shows areas in the brain involved in thinking at different depths of anesthesia. As a result of this study, the researchers expect to gain a deeper understanding of mental function during different levels of anesthesia.
Trial Details
NCT Number NCT07705022
Lead Sponsor University of Michigan
Collaborators: National Institute of General Medical Sciences (NIGMS)
Conditions Healthy, Covert Consciousness
Enrollment 60 participants
Start Date 2026-08-07
Primary Completion 2028-01 (estimated)
Study Completion 2028-01 (estimated)
Updated on ClinicalTrials.gov 2026-08-11