Clinical Trial

Safety of Topical Exosome-Containing Liquid in Healthy Volunteers

Study acronym: EV-SAFE-1
Not Yet Recruiting Phase 1
View on ClinicalTrials.gov →
Summary
This Phase 1 split-site pilot study will evaluate the safety and dermal tolerability of a topical exosome-containing liquid in 10 healthy adult volunteers. The investigational liquid will be applied to a small defined area of intact skin. A vehicle liquid without exosomes may be applied to a matched contralateral skin site as a control. The study will assess local skin reactions, systemic adverse events, vital signs, clinical laboratory parameters, and feasibility of topical administration. No burn wound or artificial skin wound will be induced in participants in this Phase 1 safety study.
Trial Details
NCT Number NCT07703969
Lead Sponsor West Kazakhstan Marat Ospanov Medical University
Conditions Skin Irritation, Healthy Volunteers
Enrollment 10 participants
Start Date 2026-09
Primary Completion 2026-12 (estimated)
Study Completion 2027-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-15