Efficacy of 5% Chitosan Nanoparticle Paste in the Treatment of Recurrent Aphthous Stomatitis

The purpose of this study is to evaluate the therapeutic clinical efficacy of a synthesized 5 wt.% chitosan nanoparticle paste compared to a standard topical corticosteroid (triamcinolone acetonide 0.1% oral paste) in patients suffering from minor recurrent aphthous stomatitis. The study specifically monitors changes in clinical ulcer diameter and pain reduction.

NCT Number	NCT07702474
Lead Sponsor	Kerman University of Medical Sciences
Conditions	Recurrent Aphthous Stomatitis, Oral Ulcers
Enrollment	30 participants
Start Date	2009-04-21
Primary Completion	2009-11-03 (estimated)
Study Completion	2009-12-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-14