Clinical Trial

Oral Nicotine Product Messaging to Communicate Risk of Use for Young Adults

Completed
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Summary
This clinical trial tests the effect of different types of oral nicotine pouch (ONP) messaging to communicate risk of using these products for young adults. Tobacco use remains the leading preventable cause of death due to cancer and other outcomes in the U.S. Tobacco products vary in the health risks they pose to users. Combustible tobacco products such as cigarettes pose higher risks than noncombustible nicotine and tobacco products such as ONPs. Despite the lower harm potential of ONPs for those who use tobacco, there are potential risks to non-users, especially susceptible young adults. Different types of messaging that include information about absolute risk and addiction, risks of ONPs relative to cigarettes and e-cigarettes, ability to use ONPs instead of cigarettes/e-cigarettes (switching), and the potential benefits of doing so and potential benefits of switching to ONPs may be more or less effective in communicating risk for young adults.
Trial Details
NCT Number NCT07702435
Lead Sponsor Ohio State University Comprehensive Cancer Center
Collaborators: National Cancer Institute (NCI)
Conditions Tobacco-Related Carcinoma
Enrollment 607 participants
Start Date 2025-08-01
Primary Completion 2025-12-29 (estimated)
Study Completion 2025-12-29 (estimated)
Updated on ClinicalTrials.gov 2026-07-14