Esketamine Versus Sufentanil for Sedation in Patients Undergoing ERCP

This study compares two anesthesia medications, esketamine and sufentanil, used together with propofol during ERCP procedures. The goal is to find out which combination provides better safety and comfort for people undergoing ERCP. Participants will be randomly assigned to receive either esketamine or sufentanil during sedation. Researchers will monitor blood oxygen levels, blood pressure, and recovery time during and after the procedure to evaluate safety and effectiveness.

NCT Number	NCT07702240
Lead Sponsor	Ren Da
Conditions	Biliary Tract Diseases, Procedural Sedation and Analgesia
Enrollment	530 participants
Start Date	2026-07-10
Primary Completion	2028-03-10 (estimated)
Study Completion	2028-03-10 (estimated)
Updated on ClinicalTrials.gov	2026-07-14