BLOCK-TRAUMA Study

This prospective cohort study will evaluate the association between the overall burden of regional anesthesia and early clinical outcomes in adult patients with polytrauma. Patients with severe trauma often experience pain from multiple injury sites and may require more than one peripheral nerve block or continuous regional anesthesia catheter. While regional anesthesia can improve pain control and reduce opioid use, multiple blocks and catheters may also increase treatment complexity, local anesthetic exposure, motor weakness, and monitoring challenges. The study will prospectively collect data on the number and type of regional anesthesia procedures, local anesthetic exposure, catheter use, pain intensity, opioid consumption, mobility, complications, and early recovery outcomes. The goal is to determine whether increasing regional anesthesia burden is associated with improved analgesia, functional recovery, or increased risk in polytrauma patients.

NCT Number	NCT07702071
Lead Sponsor	Ukrainian Society of Regional Anesthesia and Pain Therapy
Conditions	Polytrauma, Regional Anaesthesia, Nerve Block, Acute Pain, Combat Trauma
Enrollment	500 participants
Start Date	2026-07-23
Primary Completion	2026-07-23 (estimated)
Study Completion	2026-10-23 (estimated)
Updated on ClinicalTrials.gov	2026-07-14