Ionized Calcium Changes for Predicting Postoperative Hypocalcemia After Total Thyroidectomy

This prospective observational study aims to evaluate whether changes in ionized calcium levels measured by blood gas analysis during the preoperative, intraoperative, and postoperative periods can predict postoperative hypocalcemia in patients undergoing total thyroidectomy. Ionized calcium values obtained at predefined perioperative time points will be compared with postoperative biochemical and clinical hypocalcemia outcomes.

NCT Number	NCT07701824
Lead Sponsor	Emrecan Deniz
Conditions	Postoperative Hypocalcemia, Postoperative Hypoparathyroidism, Total Thyroidectomy
Enrollment	327 participants
Start Date	2025-06-12
Primary Completion	2026-04-25 (estimated)
Study Completion	2026-07-05 (estimated)
Updated on ClinicalTrials.gov	2026-07-14