Acupuncture Versus Sham Acupuncture for Tinnitus

This multicenter, randomized, sham-controlled clinical trial will evaluate the efficacy and safety of acupuncture for patients with subjective idiopathic tinnitus. A total of 226 eligible participants will be randomly assigned to receive either acupuncture or sham acupuncture. Both groups will receive treatment for 5 weeks. The primary outcome is the change in Tinnitus Handicap Inventory score from baseline to Week 5. Secondary outcomes include tinnitus loudness, tinnitus severity, sleep quality, anxiety, depression, audiological assessments, and adverse events. Exploratory neuroimaging outcomes include functional magnetic resonance imaging and magnetoencephalography measures.

NCT Number	NCT07700069
Lead Sponsor	Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University Collaborators: Shanghai University of Traditional Chinese Medicine, Longhua Hospital
Conditions	Tinnitus
Enrollment	226 participants
Start Date	2026-07-10
Primary Completion	2026-12-31 (estimated)
Study Completion	2027-03-31 (estimated)
Updated on ClinicalTrials.gov	2026-07-13