Eating Disorders in Patients With Phenylketonuria

The prevalence of eating disorders and BMI are significantly higher in PKU patients than in the general population. The protein-restricted diet associated with high carbohydrate intake and the severity of the genetic defect and disease can lead to weight gain in these patients; However, the link between restrictive diets, EDs, and obesity has not been demonstrated in patients with PKU. These issues remain poorly explored, meaning that patients may not be detected and treated.

NCT Number	NCT07698743
Lead Sponsor	Central Hospital, Nancy, France
Conditions	Phenylketonuria
Enrollment	70 participants
Start Date	2025-12-04
Primary Completion	2028-01-01 (estimated)
Study Completion	2028-04-02 (estimated)
Updated on ClinicalTrials.gov	2026-07-13