Clinical Trial

Efficacy and Safety of MegaLT Injection for Platelet Recovery After Umbilical Cord Blood Transplantation

Not Yet Recruiting Early Phase 1
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Summary
This is a single-arm, early safety and feasibility exploratory study to evaluate the efficacy and safety of MegaLT Injection in promoting platelet recovery after umbilical cord blood transplantation. Adults with malignant hematologic diseases who undergo umbilical cord blood transplantation will receive a single intravenous infusion of MegaLT Injection on day 14 after transplantation. Two dose levels will be evaluated sequentially, and platelet recovery, platelet transfusion requirements, and safety outcomes will be assessed.
Trial Details
NCT Number NCT07696767
Lead Sponsor Anhui Provincial Hospital
Conditions Thrombocytopenia, Hematologic Malignacies, Platelet Recovery After Umbilical Cord Blood Transplantation
Enrollment 7 participants
Start Date 2026-07-31
Primary Completion 2026-12-31 (estimated)
Study Completion 2027-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-10