Clinical Trial

Large Language Models Versus Anesthesiologists for ASA Physical Status Classification

Study acronym: ASA-LLM
Not Yet Recruiting
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Summary
The American Society of Anesthesiologists Physical Status (ASA-PS) classification is a cornerstone of preoperative risk assessment, yet interrater variability among clinicians is well documented. Large language models (LLMs) have recently demonstrated expert-level performance in several clinical classification tasks, including ASA-PS assignment. This retrospective observational study evaluates whether four widely used LLMs - ChatGPT, DeepSeek, Gemini, and Claude - can accurately and consistently assign ASA-PS classes from structured, fully anonymized clinical vignettes derived from real preoperative anesthesia evaluations, using a consensus of senior anesthesiologists as the reference standard. No patient data will be transmitted to third-party platforms. Clinical information will be converted by the investigators into de-identified structured vignettes containing only age range, sex, body mass index range, presence or absence of systemic diseases, functional capacity, and the major/minor nature of the planned surgery, in full compliance with national data protection legislation (KVKK).
Trial Details
NCT Number NCT07696221
Lead Sponsor Marmara University Pendik Training and Research Hospital
Conditions Anesthesia, Preoperative Risk Prediction, Preoperative Risk Assessment
Enrollment 350 participants
Start Date 2026-07-21
Primary Completion 2026-08-21 (estimated)
Study Completion 2026-10-21 (estimated)
Updated on ClinicalTrials.gov 2026-07-10