Clinical Trial

A Clinical Trial to Investigate the Efficacy and Safety of a Plant-derived Cetylated Fatty Acids (CFA) on Knee Pain and Stiffness in Healthy Adults With Persistent Knee Pain

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Summary
The goal of this clinical trial is to investigate the efficacy and safety of plant-derived cetylated fatty acids (CFA) on joint health and mobility in adults with persistent knee pain. The main question it aims to answer is what is the change from baseline to day 42 in knee joint health, as assessed by the KOOS pain sub-scale scores, between plant-derived cetylated fatty acids (CFA) and placebo? Researchers will compare plant-derived cetylated fatty acids (CFA) with placebo to evaluate its effects on joint health, mobility, pain, and stiffness. Participants will be asked to: * Consume plant-derived cetylated fatty acids (CFA) or placebo daily from Day 1 until the day before the end-of-study visit * Have height, weight, heart rate, and blood pressure measurements taken * Complete the Knee injury and Osteoarthritis Outcome Score (KOOS) questionnaire * Complete the 6-Minute Walk Test (6MWT) * Complete the 30 seconds chair sit to stand test * Complete the pain and stiffness Likert scale * Complete the subject treatment diary daily
Trial Details
NCT Number NCT07695714
Lead Sponsor Everwell Health
Collaborators: KGK Science Inc.
Conditions Joint Health, Mobility, Knee Pain
Enrollment 80 participants
Start Date 2026-07
Primary Completion 2027-01 (estimated)
Study Completion 2027-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-10