Clinical Trial

Probiotic and Prebiotic Supplementation in Peritoneal Dialysis Patients

Recruiting
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Summary
The goal of this clinical trial is to learn if synbiotics work to lower inflammation in adults with chronic kidney disease who are on peritoneal dialysis. Synbiotics are daily capsules that contain a mix of probiotics (good bacteria) and prebiotics (fiber that feeds good bacteria). The main questions it aims to answer are: Do synbiotics lower the level of inflammation markers in the blood? Do synbiotics improve the nutritional status of the participants? Do synbiotics lower the number of peritonitis (peritoneal infections) episodes? Researchers will compare synbiotics to a placebo to see if the treatment works. A placebo is a look-alike capsule that contains no active ingredients. Participants will: Take 1 capsule every day for 6 months Visit the clinic at the start, at 3 months, and at 6 months for blood tests and nutrition checkups
Trial Details
NCT Number NCT07694791
Lead Sponsor Hospital Universitario Dr. Jose E. Gonzalez
Conditions Chronic Kidney Disease (Stages 4 and 5), Peritoneal Dialysis (PD)
Enrollment 60 participants
Start Date 2025-10-03
Primary Completion 2027-06 (estimated)
Study Completion 2027-06 (estimated)
Updated on ClinicalTrials.gov 2026-07-10