Intraperitoneal Dexmedetomidine Versus Magnesium as Adjuvants to Bupivacaine in Laparoscopic Cholecystectomy

Although both dexmedetomidine and magnesium sulphate have been individually evaluated as adjuvants to local anesthetics, direct comparisons between the two agents in intraperitoneal instillation during laparoscopic cholecystectomy remain limited. Understanding their relative efficacy and safety could provide valuable guidance for optimizing perioperative analgesia in these patients.

NCT Number	NCT07693621
Lead Sponsor	Alexandria University
Conditions	Dexmedetomidine, Magnesium Sulfate, Laparoscopic Cholecystectomy
Enrollment	80 participants
Start Date	2026-05-03
Primary Completion	2026-11-03 (estimated)
Study Completion	2027-01-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-09