Clinical Trial

Topical Chinese Medicine and Exosome Mechanisms for Atopic Dermatitis

Active, Not Recruiting Phase 2
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Summary
The goal of this clinical trial is to learn if menthol works to relieve pruritus in atopic dermatitis. The primary objectives are to evaluate the safety and clinical efficacy of menthol-containing gloves and foot-covers, specifically whether they can improve patient-reported Peak Pruritus Numerical Rating Scale (PP-NRS). Secondary objectives include assessing the Eczema Area Severity Index (EASI), the Dermatology Life Quality Index (DLQI), biochemical examinations (including white blood cell count, hemoglobin, GOT, GPT, creatinine, platelet count, and HbA1c), and exosome analysis. Participants will be asked to: Wear menthol-containing gloves and foot-covers (or shams) for 5 minutes per session, following a schedule of 5 consecutive days of use and 2 days of rest each week, over a total period of 28 days. Attend clinic visits on Days 1, 14, 28, and 42 for evaluations and tests.
Trial Details
NCT Number NCT07693400
Lead Sponsor Taiwan Municipal An-Nan Hospital-China Medical University
Collaborators: China Medical University, Taiwan
Conditions Atopic Dermatitis (AD)
Enrollment 44 participants
Start Date 2026-04-29
Primary Completion 2028-02-16 (estimated)
Study Completion 2028-02-16 (estimated)
Updated on ClinicalTrials.gov 2026-07-09