Clinical Trial

A Clinical Trial to Assess the Absorption, Safety, and Efficacy of an Oral Nicotinamide Adenine Dinucleotide (NAD+) Supplement in Healthy Adults

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Summary
The goal of this clinical trial is to assess the absorption, safety, and efficacy of an NAD+ supplement in healthy adults. The main question it aims to answer is: What is the change in NAD+ levels in whole blood from baseline to day 56 between the NAD+ supplement and placebo? Researchers will compare the NAD+ supplement to placebo to evaluate its absorption, safety, and efficacy. Participants will be asked to: * Complete questionnaires * Provide blood samples * Consume either the NAD+ supplement or a placebo for 55 days * Have their endothelial function evaluated
Protocol Amendment History 2 changes
notable Primary completion pushed: 2026-12 -> 2027-03 2026-08-12
minor Completion pushed: 2026-12 -> 2027-03 2026-08-12
Trial Details
NCT Number NCT07692633
Lead Sponsor Reus Research
Collaborators: KGK Science Inc.
Conditions NAD+ Bioavailability, NAD+ Safety, NAD+ Efficacy
Enrollment 80 participants
Start Date 2026-08
Primary Completion 2027-03 (estimated)
Study Completion 2027-03 (estimated)
Updated on ClinicalTrials.gov 2026-08-11