Clinical Trial

Evaluation of the Safety of Cytokine-Induced-Killer Cells During Early Transplant Period of Autologous Hematopoietic Stem Cell Transplant Recipients.

Completed
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Summary
The goal of this clinical study is to evaluate the safety of cytokine-induced-killer (CIK) cells during early transplant period of autologous hematopoietic stem cell transplant. The main questions it aims to answer are: * What adverse events occur within 2 years following CIK infusion? * Does viral reactivation (CMV, EBV, BKV) occur and lead to infection during the early transplant period of autologous hematopoietic stem cell transplant after CIK infusion? Patients will: * Receive a single infusion of CIK at a dose of 1x10\^9 to 1x10\^10 cells either intravenously or using a central venous catheter within 14±4 days after receiving the autologous hematopoietic stem cell transplantation. * Attend follow-up visits at the clinic for 24 months after the infusion.
Trial Details
NCT Number NCT07692607
Lead Sponsor LucasBio
Conditions Autologous Hematopoietic Stem Cell Transplant
Enrollment 25 participants
Start Date 2022-03-28
Primary Completion 2025-02-11 (estimated)
Study Completion 2026-03-17 (estimated)
Updated on ClinicalTrials.gov 2026-07-09