Coronary Computed Tomography Angiography (CCTA) for the Pre-procedural Planning of Percutaneous Coronary Intervention

The CT-PLAN PCI trial will evaluate whether CCTA-guided PCI improves procedural efficiency compared with routine PCI (without pre-procedural CCTA-guidance for PCI planning) using procedural time as the primary endpoint. Key secondary outcomes will include contrast volume, radiation dose, fluoroscopy time, resource utilization, and periprocedural outcomes including post-PCI physiology, and peri-procedural myocardial injury measured by high-sensitivity cardiac troponin assays.

NCT Number	NCT07691502
Lead Sponsor	Minneapolis Heart Institute Foundation Collaborators: HeartFlow, Inc., Shockwave Medical, Inc.
Conditions	Coronary Artery Disease, CT
Enrollment	200 participants
Start Date	2026-07-15
Primary Completion	2028-07-15 (estimated)
Study Completion	2028-12-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-10