Clinical Trial

Prevalence of Chapman Reflex Points in Medical Students and Their Association With Visceral Symptoms

Completed
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Summary
Chapman Reflex Points (CRPs) are small palpable nodules found within connective tissue that have traditionally been associated with dysfunction of internal organs and the autonomic nervous system. However, little is known about how commonly these findings occur in healthy individuals or whether they are associated with symptoms experienced by otherwise healthy people. The purpose of this study is to determine the prevalence of Chapman Reflex Points in young healthy adults and to evaluate whether the presence and distribution of these points are associated with self-reported visceral symptoms. Participants complete a standardized health questionnaire regarding recent and recurrent symptoms and undergo a blinded physical examination of established Chapman Reflex Point locations performed by a trained investigator. The results of this study may improve understanding of the physiological mechanisms underlying Chapman Reflex Points and help clarify their potential role in preventive osteopathic assessment and early identification of altered autonomic, lymphatic, fascial, or neuroendocrine function.
Trial Details
NCT Number NCT07691112
Lead Sponsor The Touro College and University System
Conditions Healthy, Autonomic Nervous System Diseases, Lymphatic Diseases, Somatic Dysfunction, Chapman Reflex Points
Enrollment 101 participants
Start Date 2020-03-04
Primary Completion 2026-06-26 (estimated)
Study Completion 2026-06-27 (estimated)
Updated on ClinicalTrials.gov 2026-07-08