Clinical Trial

Embryo QUAlity in Ovarian Stimulation With hMG.

Study acronym: EQUAM
Not Yet Recruiting Phase 4
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Summary
Ovarian stimulation (OS) is a key component of IVF, aimed at increasing oocyte yield and improving embryo development potential. While early protocols relied solely on FSH, newer approaches incorporate hMG and LH-based stimulation, allowing more individualized treatments for specific patient populations. Evidence suggests that hMG and recombinant FSH (rFSH) have comparable effectiveness in stimulation outcomes, and current guidelines support the use of both. However, the impact of different gonadotropins on embryo quality remains unclear, with mixed findings across protocols. Given the increasing use of combined rFSH and hMG and the limited data in PPOS protocols, this study proposes a randomized controlled trial to compare embryo quality between two different rFSH-hMG dosing strategies.
Trial Details
NCT Number NCT07691073
Lead Sponsor Fundacion Dexeus
Collaborators: Ferring Pharmaceuticals
Conditions Infertility
Enrollment 240 participants
Start Date 2026-09
Primary Completion 2029-02 (estimated)
Study Completion 2029-05 (estimated)
Updated on ClinicalTrials.gov 2026-07-08