Clinical Trial

AI-Assisted Versus Conventional Orthodontic Diagnosis and Treatment Planning

Study acronym: AI-OrthoDx
Completed
View on ClinicalTrials.gov →
Summary
This study compared an artificial intelligence-assisted orthodontic diagnostic workflow using WebCeph with a conventional clinician-based workflow. The study included 120 new orthodontic patients treated at Ben Hafeed Dental Center in Sana'a, Yemen, between March 2024 and March 2026. For each participant, the researchers prepared a de-identified package of routine pretreatment records, including clinical findings, extraoral and intraoral photographs, panoramic and lateral cephalometric radiographs, and dental models or digital scans. The same case package was independently assessed using both the artificial intelligence-assisted and conventional workflows. An independent panel of five expert orthodontists reviewed the cases and established the reference standard. The main outcome was agreement with the expert panel for skeletal sagittal classification as Class I, Class II, or Class III. Other outcomes included orthodontic treatment-need grades, premolar extraction decisions, anchorage planning, appliance selection, and the time required to complete each diagnostic workflow. Participation did not alter the routine orthodontic care provided to patients, and final clinical decisions remained the responsibility of the treating orthodontist.
Trial Details
NCT Number NCT07690774
Lead Sponsor Ben Hafeed Dental Center
Conditions Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
Enrollment 120 participants
Start Date 2024-03-03
Primary Completion 2026-03-31 (estimated)
Study Completion 2026-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-08