Clinical Trial

Rituximab+ Zanubrutinib for Patients With Hairy Cell Leukemia and Hairy Cell Variant

Study acronym: Rituximab+ Zan
Enrolling by Invitation Phase 2
View on ClinicalTrials.gov →
Summary
investigators propose a phase II, open label-nonrandomized, single arm, multicenter study aiming to assess the safety and efficacy with the combination of Rituximab and Zanubrutinib in patients with HAIRY CELL LUKEMIA HCL, or HAIRY CELL LEUKEMIA VARIANT-HCLv.
Trial Details
NCT Number NCT07690761
Lead Sponsor Bnai Zion Medical Center
Collaborators: Meir Medical Center, Hadassah Medical Organization
Conditions Hairy Cell Leukemia, Hairy Cell Leukemia Variant
Enrollment 12 participants
Start Date 2026-06-01
Primary Completion 2028-12-31 (estimated)
Study Completion 2033-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-08