Clinical Trial

Tear Biomarkers for Migraine

Study acronym: TEAR
Not Yet Recruiting
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Summary
The goal of this observational monocentric study is to investigate tear and serum biomarkers in patients with migraine compared with healthy controls, and to explore their potential diagnostic, clinical, and predictive value. In addition to the cross-sectional evaluation, a longitudinal subgroup analysis will be conducted to assess biomarker changes over time during treatment with anti- Calcitonin Gene-Related Peptide (anti-CGRP) therapies.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-07-01.
Trial Details
NCT Number NCT07690696
Lead Sponsor Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Conditions Migraine
Enrollment 400 participants
Start Date 2026-09-30
Primary Completion 2029-09-29 (estimated)
Study Completion 2029-09-29 (estimated)
Updated on ClinicalTrials.gov 2026-07-10