Clinical Trial

Machine Learning-Based Risk Identification and Precision Exercise for Common Running Injuries

Completed
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Summary
This study aims to identify biomechanical risk factors associated with common running-related injuries in recreational runners using machine learning analysis. It also aims to evaluate whether a precision exercise intervention based on these risk factors can improve injury-related biomechanical and kinematic outcomes. The main questions it aims to answer are: Which biomechanical features identified by machine learning are associated with the occurrence of common running-related injuries, including medial tibial stress syndrome (MTSS), patellofemoral pain (PFP), and chronic Achilles tendinopathy? Whether a precision exercise intervention based on these risk factors can improve injury-related biomechanical and kinematic characteristics? Participants will: Undergo baseline biomechanical assessment during running, including motion capture, ground reaction force, and surface electromyography Be prospectively followed for 6 months to record the occurrence of running-related injuries Be classified into injury groups based on diagnosis, including MTSS, PFP, and chronic Achilles tendinopathy Following the completion of the follow-up period, participants will be allocated to either a precision multidimensional intervention group, a precision exercise intervention group, or a control group. The precision multidimensional intervention group will receive patient education in addition to an 8-week intervention program, including stretching, strength training, and real-time movement feedback. The precision exercise intervention group will receive the same 8-week intervention program, consisting of stretching, strength training, and real-time movement feedback. The control group will maintain their habitual physical activity patterns without receiving any additional intervention. Participants will be reassessed after the intervention and at the 3-month follow-up using the same biomechanical testing protocol.
Trial Details
NCT Number NCT07689916
Lead Sponsor Zeyi Zhang
Conditions Running-related Injuries, Medial Tibial Stress Syndrome, Patellofemoral Pain, PFP, Chronic Achilles Tendinopathy
Enrollment 204 participants
Start Date 2025-08-01
Primary Completion 2026-01-01 (estimated)
Study Completion 2026-02-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-08