Clinical Trial

Ultrasound-Guided Intermediate Cervical Plexus Block for Postoperative Analgesia in Vagus Nerve Stimulation Surgery

Completed
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Summary
This prospective, randomized, double-blind, placebo-controlled clinical trial aims to evaluate the analgesic efficacy of ultrasound-guided intermediate cervical plexus block (ICB) in patients undergoing vagus nerve stimulation (VNS) implantation surgery under general anesthesia. Participants are randomly assigned to receive either an ultrasound-guided ICB with 10 mL of 0.25% bupivacaine or a placebo injection with 10 mL of normal saline following induction of general anesthesia. The primary outcome is total postoperative morphine consumption during the first 24 hours after surgery. Secondary outcomes include intraoperative remifentanil consumption, postoperative pain intensity assessed using the Numeric Rating Scale (NRS), time to first analgesic request, length of hospital stay, and postoperative seizure incidence.
Trial Details
NCT Number NCT07689617
Lead Sponsor Firat University
Conditions Drug-Resistant Epilepsy, Epilepsy, Vagus Nerve Stimulation
Enrollment 52 participants
Start Date 2022-05-01
Primary Completion 2023-05-01 (estimated)
Study Completion 2023-05-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-08