Clinical Trial

Exercise Interventions for Overweight Men With Chronic Low Back Pain

Study acronym: MAMS-CLBP
Not Yet Recruiting
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Summary
This randomized controlled trial aims to compare the effectiveness of motor control exercise, aerobic walking exercise, and muscle strengthening exercise in overweight male adults with non-specific chronic low back pain and central sensitization. A total of 156 participants will be randomly assigned to one of four groups: motor control exercise plus patient education, aerobic walking exercise plus patient education, muscle strengthening exercise plus patient education, or patient education only. The interventions will be delivered over 12 weeks. The primary outcome is conditioned pain modulation (CPM), which reflects endogenous pain inhibitory function. Secondary outcomes include pain intensity, disability, health-related quality of life, executive function, and isometric trunk muscle strength. Body weight and body mass index will also be assessed as exploratory variables. Outcomes will be evaluated at baseline, immediately after the 12-week intervention, and at 6-month follow-up.
Trial Details
NCT Number NCT07688564
Lead Sponsor Universiti Sains Malaysia
Conditions Non-specific Chronic Low Back Pain, Central Sensitization
Enrollment 156 participants
Start Date 2026-07-05
Primary Completion 2026-11-05 (estimated)
Study Completion 2027-04-05 (estimated)
Updated on ClinicalTrials.gov 2026-07-07