Clinical Trial

Objective Response Rate of Ivonescimab With Chemotherapy in Locally Advanced Resectable Oral and Oropharyngeal Squamous Cell Carcinoma

Name: Objective Response Rate of Ivonescimab With Chemotherapy in Locally Advanced Resectable Oral and Oropharyngeal Squamous Cell Carcinoma — clinical trial record (NCT07686575)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Recruiting

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Summary

To investigate the neoadjuvant chemoimmunotherapy regimen of Ivonescimab combined with chemotherapy (Paclitaxel plus Cisplatin/Carboplatin) for the treatment of locally advanced resectable oral squamous cell carcinoma and oropharyngeal squamous cell carcinoma.

Trial Details

NCT Number	NCT07686575
Lead Sponsor	Zhujiang Hospital
Conditions	HNSCC, OSCC, OPSCC, Ivonescimab
Enrollment	20 participants
Start Date	2026-01-26
Primary Completion	2026-08-30 (estimated)
Study Completion	2028-08-30 (estimated)
Updated on ClinicalTrials.gov	2026-07-07