Precision Management of Urinary Tract Symptoms in Older Women

This project aims to improve the diagnosis and management of urinary tract symptoms in older women by comparing three common treatment strategies-empiric antibiotics, urinalysis-guided therapy, and culture-directed care-in a randomized trial. By integrating patient-reported outcomes, laboratory data, the study will identify which patients benefit from antibiotics and which can safely avoid them. Findings will inform precision care strategies and promote antibiotic stewardship while improving symptom outcomes and quality of life in this high-risk population.

NCT Number	NCT07686055
Lead Sponsor	Megan Bradley Collaborators: American Association of Obstetricians and Gynecologists Foundation (AAOGF)
Conditions	Urinary Tract Infection (Diagnosis)
Enrollment	90 participants
Start Date	2026-07-14
Primary Completion	2027-02-01 (estimated)
Study Completion	2027-02-14 (estimated)
Updated on ClinicalTrials.gov	2026-07-07