Clinical Trial

Upper vs Lower Extremity BP in Spinal Cesarean Using ClearSight

Recruiting
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Summary
This is a single-center, prospective observational study in patients undergoing cesarean delivery under spinal or combined spinal-epidural anesthesia. It compares whether continuous noninvasive hemodynamic measurements from the lower extremity (toe) better predict neonatal outcomes than upper extremity (arm/finger) measurements during spinal-induced hypotension. Participants receive standard spinal anesthesia and routine blood pressure management, with additional monitoring using the ClearSight™ system at both upper and lower extremities from before spinal anesthesia through delivery. The primary outcome is a composite of neonatal outcomes (APGAR scores, need for respiratory support, cord gases, and NICU admission). Secondary outcomes include maternal side effects and comfort. Overall, the study evaluates whether lower-extremity hemodynamic monitoring improves detection of clinically relevant hypotension and prediction of neonatal outcomes compared to traditional arm measurements.
Trial Details
NCT Number NCT07685730
Lead Sponsor Ohio State University
Conditions Anesthesia, Pregnancy Related, Blockades Neuromuscular
Enrollment 327 participants
Start Date 2025-02-06
Primary Completion 2029-02-06 (estimated)
Study Completion 2029-08-06 (estimated)
Updated on ClinicalTrials.gov 2026-07-06