Self-Compassion and Quality of Life in Nursing Students With Premenstrual Syndrome

Premenstrual syndrome (PMS) is one of the most common menstrual disorders among women of reproductive age and is characterized by recurrent physical, emotional, cognitive, and behavioral symptoms during the late luteal phase of the menstrual cycle. These symptoms may adversely affect academic performance, daily functioning, interpersonal relationships, and quality of life. Although previous studies have demonstrated that greater premenstrual symptom severity is associated with poorer quality of life, the psychological mechanisms underlying this relationship remain unclear. Self-compassion, defined as a compassionate and nonjudgmental attitude toward oneself during times of difficulty, has been identified as a protective psychological factor associated with better emotional well-being and adaptive coping. However, its mediating role in the relationship between premenstrual symptom severity and premenstrual syndrome-specific quality of life has not been adequately investigated. This cross-sectional study aims to examine the association between premenstrual symptom severity and premenstrual syndrome-specific quality of life and to investigate the mediating role of self-compassion among nursing students who meet the study criteria for PMS (Premenstrual Syndrome Scale score ≥110).

NCT Number	NCT07684638
Lead Sponsor	Acibadem University
Conditions	Premenstrual Syndrome, Quality of Life, Self Compassion
Enrollment	164 participants
Start Date	2026-06-26
Primary Completion	2026-07-15 (estimated)
Study Completion	2026-07-15 (estimated)
Updated on ClinicalTrials.gov	2026-07-21