Sequential PVP-I and FV

This prospective cohort study in children will determine if: topical povidone iodine 10% followed by topical fluoride varnish is superior to placebo iodine followed two different varnishes alone to prevent tooth decay (dental caries).

NCT Number	NCT07683910
Lead Sponsor	Advantage Silver Dental Arrest, LLC Collaborators: Universidad Nacional del Altiplano de Puno, University of Washington
Conditions	Dental Caries
Enrollment	393 participants
Start Date	2026-09-01
Primary Completion	2028-09-30 (estimated)
Study Completion	2029-03-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-06