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Respiratory Physiotherapy and Hospitalization in Infants With Bronchiolitis

Study acronym: BVA-RESP
StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 32 days later Jul 2027 → Sep 2027
See other at-risk trials from University of Sao Paulo

Record History

  1. Notable Recruitment opened Primary completion pushed from Jul 2027 to Sep 2027 · Start date changed from estimate of Jul 2026 to Aug 8, 2026 · Eligibility criteria expanded, about 9 words · 2 more Show 5 more changesShow less
    • Primary completion pushed from Jul 2027 to Sep 2027
    • Start date changed from estimate of Jul 2026 to Aug 8, 2026
    • Eligibility criteria expanded, about 9 words
    • Site details revised
    • Publications: details revised at 6 of 6 entries
  2. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Acute Viral Bronchiolitis (AVB) is one of the leading causes of respiratory illness and hospitalization among infants during the first year of life, generating a substantial burden on healthcare services and public health expenditures. Despite the widespread use of respiratory physiotherapy in clinical practice, there is limited evidence regarding its effectiveness in preventing hospital admissions when provided in an outpatient setting. This quasi-experimental study aims to evaluate the impact of an outpatient respiratory physiotherapy protocol on hospitalization rates among infants up to 12 months of age diagnosed with mild to moderate acute viral bronchiolitis in the public healthcare system of Sorocaba, Brazil. Infants referred for respiratory physiotherapy will be compared with a similar group of infants who receive standard medical care without physiotherapy referral. The physiotherapy protocol includes slow expiratory techniques, rhinopharyngeal retrograde clearance, cough stimulation, and continuous positive airway pressure (CPAP) when clinically indicated. Participants will be followed through medical records and telephone monitoring. The primary outcome is hospital admission due to bronchiolitis. Secondary outcomes include length of hospital stay, healthcare costs, and clinical evolution. The findings may provide evidence on whether outpatient respiratory physiotherapy can reduce hospitalizations and optimize healthcare resource utilization in infants with acute viral bronchiolitis.
Trial Details
NCT Number NCT07682844
Lead Sponsor University of Sao Paulo
Conditions Acute Viral Bronchiolitis
Enrollment 1,000 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov