STSC-HybridAPC Trial

Margin thermal ablation after piecemeal EMR significantly reduces recurrence of large colorectal polyps. As recurrence rates are now low, the key implementation question relates to efficiency and reproducibility of different ablation techniques. This randomized controlled trial compares snare tip soft coagulation (STSC) with Hybrid APC (ERBE), with procedural time as the primary endpoint.

NCT Number	NCT07682805
Lead Sponsor	Western Sydney Local Health District
Conditions	Colon Adenomas, Colon Adenomatous Polyp
Enrollment	140 participants
Start Date	2027-01-01
Primary Completion	2027-08-01 (estimated)
Study Completion	2027-08-15 (estimated)
Updated on ClinicalTrials.gov	2026-07-06