Clinical Trial

EFFECT OF PLATELET CONCENTRATE TRANSFUSION ON MICROCIRCULATORY ENDOTHELIAL FUNCTION IN INTENSIVE CARE UNIT

Study acronym: PLATOMIR
Not Yet Recruiting
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Summary
This study aims to investigate the impact of platelet concentrate (PC) transfusions on endothelial function and the systemic inflammatory response in thrombopenic patients admitted to intensive care who require prophylactic platelet transfusions. Endothelial function will be measured using a laser Doppler device coupled with an acetylcholine iontophoresis system that is applied to the skin.
Trial Details
NCT Number NCT07682246
Lead Sponsor Assistance Publique - Hôpitaux de Paris
Conditions Thrombocytopenia, Prophylactic Platelet Transfusion, Platelet Transfusion, Endothelial Function
Enrollment 60 participants
Start Date 2026-07
Primary Completion 2027-07 (estimated)
Study Completion 2027-07 (estimated)
Updated on ClinicalTrials.gov 2026-07-02