DIVision of the Interlobar Fissure in Patients Who Do Not Respond to Endobronchial Lung Volume Reduction

Surgical division of fissure is hypothesized to be safe and feasible. However, there is no preparatory study to test this hypothesis. It is logically expected that morbidity from the procedure could be less than standard LVRS and in preparation to a side-to-side trial of fissure division versus standard LVRS, a safety and feasibility study is required to test this hypothesis and inform future trial design.

NCT Number	NCT07682168
Lead Sponsor	Rocco Bilancia
Conditions	Chronic Obstructive Pulmonary Disease (COPD), Emphysema, Lung Volume Reduction Surgery
Enrollment	15 participants
Start Date	2026-08
Primary Completion	2027-08 (estimated)
Study Completion	2028-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-02