Betamethasone vs Dextrose Injections in Trigger Finger

This study aims to compare the effectiveness of ultrasound-guided betamethasone and dextrose injections in patients with trigger finger. Trigger finger is a common hand condition characterized by pain, clicking, and locking of the finger due to tendon entrapment at the A1 pulley. Corticosteroid injections are widely used as a first-line treatment; however, they may be associated with potential side effects. Dextrose injection is an alternative treatment that may promote tissue healing through regenerative mechanisms. However, there is limited high-quality evidence regarding its effectiveness in trigger finger. In this randomized controlled trial, patients will be assigned to receive either betamethasone or dextrose injection under ultrasound guidance. The primary outcome will be pain intensity measured by the Numeric Rating Scale (NRS). Secondary outcomes will include triggering severity, hand function, grip and pinch strength, and fine motor skills evaluated over a 12-week follow-up period. The results of this study may help determine whether dextrose injection is a safe and effective alternative to corticosteroid treatment in trigger finger.

NCT Number	NCT07681804
Lead Sponsor	Istanbul University - Cerrahpasa
Conditions	Trigger Finger
Enrollment	42 participants
Start Date	2026-06-30
Primary Completion	2027-04 (estimated)
Study Completion	2027-05 (estimated)
Updated on ClinicalTrials.gov	2026-07-28