Clinical Trial

Ventilation Mode and Atelectasis After Prone-Position Surgery: A Lung Ultrasound Study

Study acronym: VENTI-PRONE
Completed
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Summary
This prospective single-centre observational study compared two intraoperative mechanical ventilation modes, volume-controlled ventilation (VCV) and VCV with AutoFlow/AF, in adults undergoing elective surgery in the prone position. The ventilation mode was selected by the attending anaesthesiologist as part of routine clinical care; the investigators did not assign it. Perioperative atelectasis was assessed using a modified bilateral 12-zone lung ultrasound score obtained before induction of anaesthesia and after extubation, and oxygenation was assessed using the alveolar-arterial oxygen gradient calculated from an intraoperative arterial blood gas sample. The study also examined whether the effect of ventilation mode on atelectasis differed according to obesity.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-06-26.
Trial Details
NCT Number NCT07680881
Lead Sponsor Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Conditions Pulmonary Atelectasis, Postoperative, Postoperative Pulmonary Complications
Enrollment 90 participants
Start Date 2024-03-01
Primary Completion 2024-10-30 (estimated)
Study Completion 2024-10-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-29