Neurophysiological and Sleep-Related Effects of a Cosmetic Shampoo and Conditioner in Adults With Scalp Discomfort

The goal of this clinical trial is to learn whether regular use of Nizoral® Daily Prevent shampoo and conditioner can improve scalp comfort, sleep experiences, mood, and overall well-being in adults who have scalp discomfort and difficulty sleeping. The main questions it aims to answer are: 1. Does using the shampoo and conditioner improve scalp comfort and reduce the impact of scalp discomfort on daily life? 2. Does using the shampoo and conditioner improve sleep experiences and how rested participants feel? 3. Does using the shampoo and conditioner affect mood and other measures of well-being?. Participants completed a one-week period without hair products, followed by two weeks of using the study shampoo and conditioner at least three times per week. During the study, participants: 1. Attended weekly study visits. 2. Answered questions about their scalp comfort, sleep, and daily experiences. 3. Wore a wrist-based sleep tracking device throughout the study. Completed weekly questionnaires about sleep and scalp health. 4. Took part in non-invasive brain activity measurements during study visits.

NCT Number	NCT07680608
Lead Sponsor	Zentrela Inc. Collaborators: Thornton & Ross
Conditions	Dandruff
Enrollment	21 participants
Start Date	2025-11-07
Primary Completion	2026-02-07 (estimated)
Study Completion	2026-02-07 (estimated)
Updated on ClinicalTrials.gov	2026-07-06