Propofol-sevoflurane Induction for Pediatric Nasotracheal Intubation.

Pediatric anesthesia differs significantly from adult anesthesia due to physiological differences and increased sensitivity to anesthetic agents. In surgeries requiring nasotracheal intubation, such as dental and maxillofacial procedures, achieving optimal intubation conditions while minimizing pharmacological exposure is of considerable importance. The combination of propofol and sevoflurane is frequently preferred in pediatric anesthesia because it provides rapid induction and stable hemodynamic conditions. Therefore, this randomized controlled trial aims to evaluate nasotracheal intubation conditions following propofol-sevoflurane induction with reduced pharmacological exposure in pediatric patients. The study is expected to contribute to clinical practice by enhancing patient safety while reducing anesthetic drug use.

NCT Number	NCT07680400
Lead Sponsor	Bezmialem Vakif University
Conditions	Intubating Conditions
Enrollment	160 participants
Start Date	2026-07-10
Primary Completion	2026-07-29 (estimated)
Study Completion	2026-07-29 (estimated)
Updated on ClinicalTrials.gov	2026-07-30